Fine mapping of the HLA locus in Parkinson’s disease in Europeans

We fine mapped the leukocyte antigen (HLA) region in 13,770 Parkinson’s disease (PD) patients, 20,214 proxy-cases, and 490,861 controls of European origin. Four HLA types were associated with PD after correction for multiple comparisons, HLA-DQA1*03:01, HLA-DQB1*03:02, HLA-DRB1*04:01, and HLA-DRB1*0...

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Detalles Bibliográficos
Autores principales: Yu, Eric, Ambati, Aditya, Andersen, Maren Stolp, Krohn, Lynne, Estiar, Mehrdad A., Saini, Prabhjyot, Senkevich, Konstantin, Sosero, Yuri L., Sreelatha, Ashwin Ashok Kumar, Ruskey, Jennifer A., Asayesh, Farnaz, Spiegelman, Dan, Toft, Mathias, Viken, Marte K., Sharma, Manu, Blauwendraat, Cornelis, Pihlstrøm, Lasse, Mignot, Emmanuel, Gan-Or, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455634/
https://www.ncbi.nlm.nih.gov/pubmed/34548497
http://dx.doi.org/10.1038/s41531-021-00231-5

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