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Cyp2c44 epoxygenase-derived epoxyeicosatrienoic acids in vascular smooth muscle cells elicit vasoconstriction of the murine ophthalmic artery

Cytochrome P450 (CYP) signalling pathway has been shown to play a vital role in the vasoreactivity of wild type mouse ophthalmic artery. In this study, we determined the expression, vascular responses and potential mechanisms of the CYP-derived arachidonic acid metabolites. The expression of murine...

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Detalles Bibliográficos
Autores principales: Hu, Jiong, Sisignano, Marco, Brecht, Roman, Perumal, Natarajan, Angioni, Carlo, Bibli, Iris-Sofia, Fisslthaler, Beate, Kleinert, Hartmut, Pfeiffer, Norbert, Fleming, Ingrid, Manicam, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455677/
https://www.ncbi.nlm.nih.gov/pubmed/34548575
http://dx.doi.org/10.1038/s41598-021-98236-w