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Nicorandil Inhibits Osteoclast Formation Base on NF-κB and p-38 MAPK Signaling Pathways and Relieves Ovariectomy-Induced Bone Loss

Osteolytic bone disorders are characterized by an overall reduction in bone mineral density which enhances bone ductility and vulnerability to fractures. This disorder is primarily associated with superabundant osteoclast formation and bone resorption activity. Nicorandil (NIC) is a vasodilatory ant...

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Detalles Bibliográficos
Autores principales:	Xu, Shenggui, Cao, Xiankun, Yu, Zhenxing, He, Wenxin, Pang, Yichuan, Lin, Wang, Chen, Zhiqian, Guo, Weizhong, Lu, Xiongwei, Lin, Chengshou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455841/ https://www.ncbi.nlm.nih.gov/pubmed/34566650 http://dx.doi.org/10.3389/fphar.2021.726361

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