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Depletion of Demethylase KDM6 Enhances Early Neuroectoderm Commitment of Human PSCs

Epigenetic modifications play a crucial role in neurogenesis, learning, and memory, but the study of their role in early neuroectoderm commitment from pluripotent inner cell mass is relatively lacking. Here we utilized the system of directed neuroectoderm differentiation from human embryonic stem ce...

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Detalles Bibliográficos
Autores principales: Meng, Yajing, Zhang, Tianzhe, Zheng, Ran, Ding, Song, Yang, Jie, Liu, Ran, Jiang, Yingan, Jiang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455897/
https://www.ncbi.nlm.nih.gov/pubmed/34568320
http://dx.doi.org/10.3389/fcell.2021.702462

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