Cargando…
Gender and the Sex Hormone Estradiol Affect Multiple Sclerosis Risk Gene Expression in Epstein-Barr Virus-Infected B Cells
Multiple Sclerosis (MS) is a complex immune-mediated disease of the central nervous system. Treatment is based on immunomodulation, including specifically targeting B cells. B cells are the main host for the Epstein-Barr Virus (EBV), which has been described as necessary for MS development. Over 200...
Autores principales: | Keane, Jeremy T., Afrasiabi, Ali, Schibeci, Stephen D., Fewings, Nicole, Parnell, Grant P., Swaminathan, Sanjay, Booth, David R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8455923/ https://www.ncbi.nlm.nih.gov/pubmed/34566997 http://dx.doi.org/10.3389/fimmu.2021.732694 |
Ejemplares similares
-
The Interaction of Human and Epstein–Barr Virus miRNAs with Multiple Sclerosis Risk Loci
por: Afrasiabi, Ali, et al.
Publicado: (2021) -
The interaction of Epstein-Barr virus encoded transcription factor EBNA2 with multiple sclerosis risk loci is dependent on the risk genotype
por: Keane, Jeremy Thomas, et al.
Publicado: (2021) -
Evidence from genome wide association studies implicates reduced control of Epstein-Barr virus infection in multiple sclerosis susceptibility
por: Afrasiabi, Ali, et al.
Publicado: (2019) -
The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis
por: Afrasiabi, Ali, et al.
Publicado: (2020) -
The interaction between Epstein–Barr virus and multiple sclerosis genetic risk loci: insights into disease pathogenesis and therapeutic opportunities
por: Afrasiabi, Ali, et al.
Publicado: (2023)