Generation of Pure Highly Functional Human Anti-Tumor Specific Cytotoxic T Lymphocytes With Stem Cell-Like Memory Features for Melanoma Immunotherapy

Adoptive immunotherapy based on the transfer of anti-tumor cytotoxic T lymphocytes (CTLs) is a promising strategy to cure cancers. However, rapid expansion of numerous highly functional CTLs with long-lived features remains a challenge. Here, we constructed NIH/3T3 mouse fibroblast-based artificial...

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Detalles Bibliográficos
Autores principales: Hamieh, Mohamad, Chatillon, Jean-François, Dupel, Estelle, Bayeux, Florence, Fauquembergue, Emilie, Maby, Pauline, Drouet, Aurelie, Duval-Modeste, Anne-Bénédicte, Adriouch, Sahil, Boyer, Olivier, Latouche, Jean-Baptiste
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456028/
https://www.ncbi.nlm.nih.gov/pubmed/34566953
http://dx.doi.org/10.3389/fimmu.2021.674276

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