Ca(2+) and Membrane Potential Transitions During Action Potentials Are Self-Similar to Each Other and to Variability of AP Firing Intervals Across the Broad Physiologic Range of AP Intervals During Autonomic Receptor Stimulation

Ca(2+) and V(m) transitions occurring throughout action potential (AP) cycles in sinoatrial nodal (SAN) cells are cues that (1) not only regulate activation states of molecules operating within criticality (Ca(2+) domain) and limit-cycle (V(m) domain) mechanisms of a coupled-clock system that underl...

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Detalles Bibliográficos
Autores principales: Yang, Dongmei, Morrell, Christopher H., Lyashkov, Alexey E., Tagirova Sirenko, Syevda, Zahanich, Ihor, Yaniv, Yael, Vinogradova, Tatiana M., Ziman, Bruce D., Maltsev, Victor A., Lakatta, Edward G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456031/
https://www.ncbi.nlm.nih.gov/pubmed/34566668
http://dx.doi.org/10.3389/fphys.2021.612770

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