Platelets induce free and phospholipid-esterified 12-hydroxyeicosatetraenoic acid generation in colon cancer cells by delivering 12-lipoxygenase

Platelets promote tumor metastasis by inducing promalignant phenotypes in cancer cells and directly contributing to cancer-related thrombotic complications. Platelet-derived extracellular vesicles (EVs) can promote epithelial-mesenchymal transition (EMT) in cancer cells, which confers high-grade mal...

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Detalles Bibliográficos
Autores principales: Contursi, Annalisa, Schiavone, Simone, Dovizio, Melania, Hinz, Christine, Fullone, Rosa, Tacconelli, Stefania, Tyrrell, Victoria J., Grande, Rosalia, Lanuti, Paola, Marchisio, Marco, Zucchelli, Mirco, Ballerini, Patrizia, Lanas, Angel, O'Donnell, Valerie B., Patrignani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456051/
https://www.ncbi.nlm.nih.gov/pubmed/34428433
http://dx.doi.org/10.1016/j.jlr.2021.100109

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