Cargando…

Tumor Mutation Burden-Associated LINC00638/miR-4732-3p/ULBP1 Axis Promotes Immune Escape via PD-L1 in Hepatocellular Carcinoma

Tumor mutation burden (TMB) is associated with immune infiltration, while its underlying mechanism in hepatocellular carcinoma (HCC) remains unclear. A long noncoding RNA (lncRNA)-related competitive endogenous RNA (ceRNA) network can regulate various tumor behaviors, and research about its correlat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qi, Feng, Du, Xiaojing, Zhao, Zhiying, Zhang, Ding, Huang, Mengli, Bai, Yuezong, Yang, Biwei, Qin, Wenxing, Xia, Jinglin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456090/ https://www.ncbi.nlm.nih.gov/pubmed/34568062 http://dx.doi.org/10.3389/fonc.2021.729340

Ejemplares similares

LINC00638 promotes the progression of non-small cell lung cancer by regulating the miR-541-3p/IRS1/PI3K/Akt axis
por: Zhang, Juan, et al.
Publicado: (2023)

LINC00638/hsa-miR-29b-3p axis-mediated high expression of CDCA4 correlates with tumor immune infiltration and hepatocellular carcinoma progression
por: Wang, Bo, et al.
Publicado: (2023)

Overexpression of long noncoding RNA LINC00638 inhibits inflammation and oxidative stress in rheumatoid arthritis fibroblast‐like synoviocytes by regulating the Nrf2/HO‐1 pathway
por: Sun, Yanqiu, et al.
Publicado: (2022)

Gemcitabine inhibits immune escape of pancreatic cancer by down regulating the soluble ULBP2 protein
por: Lin, Xiansheng, et al.
Publicado: (2016)

Draft genome of the Ogataea polymorpha type strain CBS 4732
por: Collins, Joseph H., et al.
Publicado: (2023)

Diversity of ULBP5 in Old-World monkeys (Cercopithecidae) and divergence of the ULBP gene family in primates
por: NARUSE, Taeko K., et al.
Publicado: (2018)

LncRNA TYMSOS facilitates breast cancer metastasis and immune escape through downregulating ULBP3
por: Zhang, Ke-Jing, et al.
Publicado: (2023)

miR‑4732‑5p promotes ovarian cancer mobility by targeting MCUR1
por: Li, Xin, et al.
Publicado: (2023)

ULBP1 Is Elevated in Human Hepatocellular Carcinoma and Predicts Outcome
por: Easom, Nicholas J. W., et al.
Publicado: (2020)

Immune ULBP1 is Elevated in Colon Adenocarcinoma and Predicts Prognosis
por: Ruan, Guo-Tian, et al.
Publicado: (2022)

An Immunosensor for the Detection of ULBP2 Biomarker
por: Yang, Wen-Chi, et al.
Publicado: (2020)

Genomic organization and evolution of the ULBP genes in cattle
por: Larson, Joshua H, et al.
Publicado: (2006)

ULBPs: regulators of human lymphocyte stress recognition
por: Zuo, Jianmin, et al.
Publicado: (2017)

Natural Killer Cell-Mediated Shedding of ULBP2
por: Wang, Ruipeng, et al.
Publicado: (2014)

Expression and prognostic significance of unique ULBPs in pancreatic cancer
por: Chen, Jiong, et al.
Publicado: (2016)

miR‐4732‐5p promotes breast cancer progression by targeting TSPAN13
por: Wang, Ya‐Wen, et al.
Publicado: (2019)

Expression and clinical significance of LAG-3, FGL1, PD-L1 and CD8(+)T cells in hepatocellular carcinoma using multiplex quantitative analysis
por: Guo, Mengzhou, et al.
Publicado: (2020)

Cellular Expression, Trafficking, and Function of Two Isoforms of Human ULBP5/RAET1G
por: Eagle, Robert A., et al.
Publicado: (2009)

Implicit and Explicit Weight Bias in a National Sample of 4732 Medical Students: The Medical Student CHANGES Study
por: Phelan, Sean M., et al.
Publicado: (2014)

The NKG2D ligand ULBP4 is not expressed by human monocytes
por: Lazarova, Mariya, et al.
Publicado: (2021)

Correction: Cellular Expression, Trafficking, and Function of Two Isoforms of Human ULBP5/RAET1G
por: Eagle, Robert A., et al.
Publicado: (2009)

Correction: Cellular Expression, Trafficking, and Function of Two Isoforms of Human ULBP5/RAET1G
por: Eagle, Robert A., et al.
Publicado: (2009)

LncRNA00638 promotes the osteogenic differentiation of periodontal mesenchymal stem cells from periodontitis patients under static mechanical strain
por: Zhang, Xiaochen, et al.
Publicado: (2023)

miR-4732-3p in Extracellular Vesicles From Mesenchymal Stromal Cells Is Cardioprotective During Myocardial Ischemia
por: Sánchez-Sánchez, Rafael, et al.
Publicado: (2021)

MICA/B and ULBP1 NKG2D ligands are independent predictors of good prognosis in cervical cancer
por: Cho, Hanbyoul, et al.
Publicado: (2014)

Plasma-derived exosomal miR-4732-5p is a promising noninvasive diagnostic biomarker for epithelial ovarian cancer
por: Liu, Jingjing, et al.
Publicado: (2021)

Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape
por: Jiang, Xianjie, et al.
Publicado: (2019)

A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells
por: Gowen, Benjamin G, et al.
Publicado: (2015)

Epithelial‐mesenchymal transition may be involved in the immune evasion of circulating gastric tumor cells via downregulation of ULBP1
por: Hu, Baoguang, et al.
Publicado: (2020)

Full-Length Genome of an Ogataea polymorpha Strain CBS4732 ura3Δ Reveals Large Duplicated Segments in Subtelomeric Regions
por: Chang, Jia, et al.
Publicado: (2022)

Chromosome 11q13 amplification correlates with poor response and prognosis to PD-1 blockade in unresectable hepatocellular carcinoma
por: Yan, Kai, et al.
Publicado: (2023)

ULBP1 is induced by hepatitis C virus infection and is the target of the NK cell‐mediated innate immune response in human hepatocytes
por: Dansako, Hiromichi, et al.
Publicado: (2018)

Secretome-Based Identification of ULBP2 as a Novel Serum Marker for Pancreatic Cancer Detection
por: Chang, Ya-Ting, et al.
Publicado: (2011)

PD-L1/PD-1 Axis in Glioblastoma Multiforme
por: Litak, Jakub, et al.
Publicado: (2019)

The PD-1:PD-L1 axis in Inflammatory Arthritis
por: Canavan, Mary, et al.
Publicado: (2021)

PD-1/PD-L1 axis in organ fibrosis
por: Zhao, Youliang, et al.
Publicado: (2023)

Downregulation of the stress-induced ligand ULBP1 following SV40 infection confers viral evasion from NK cell cytotoxicity
por: Bauman, Yoav, et al.
Publicado: (2016)

Roles of CXCL5 on migration and invasion of liver cancer cells
por: Xu, Xiaojing, et al.
Publicado: (2014)

Targeting the PD-1/PD-L1 Axis in Human Vitiligo
por: Willemsen, Marcella, et al.
Publicado: (2020)

Development of Radiotracers for Imaging of the PD-1/PD-L1 Axis
por: Krutzek, Fabian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rshc162v925k3u2plslpg8retj