Altered regulation of DPF3, a member of the SWI/SNF complexes, underlies the 14q24 renal cancer susceptibility locus

Our study investigated the underlying mechanism for the 14q24 renal cell carcinoma (RCC) susceptibility risk locus identified by a genome-wide association study (GWAS). The sentinel single-nucleotide polymorphism (SNP), rs4903064, at 14q24 confers an allele-specific effect on expression of the doubl...

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Detalles Bibliográficos
Autores principales: Colli, Leandro M., Jessop, Lea, Myers, Timothy A., Camp, Sabrina Y., Machiela, Mitchell J., Choi, Jiyeon, Cunha, Renato, Onabajo, Olusegun, Mills, Grace C., Schmid, Virginia, Brodie, Seth A., Delattre, Olivier, Mole, David R., Purdue, Mark P., Yu, Kai, Brown, Kevin M., Chanock, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456159/
https://www.ncbi.nlm.nih.gov/pubmed/34390653
http://dx.doi.org/10.1016/j.ajhg.2021.07.009

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