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The kidney hepcidin/ferroportin axis controls iron reabsorption and determines the magnitude of kidney and systemic iron overload
The hepcidin/ferroportin axis controls systemic iron homeostasis by regulating iron acquisition from the duodenum and reticuloendothelial system, respective sites of iron absorption and recycling. Ferroportin is also abundant in the kidney, where it has been implicated in tubular iron reabsorption....
Autores principales: | Mohammad, Goran, Matakidou, Athena, Robbins, Peter A., Lakhal-Littleton, Samira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456337/ https://www.ncbi.nlm.nih.gov/pubmed/33991530 http://dx.doi.org/10.1016/j.kint.2021.04.034 |
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