Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery

SUMMARY: Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Roche, Christopher D, Brereton, Russell J L, Ashton, Anthony W, Jackson, Christopher, Gentile, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456486/
https://www.ncbi.nlm.nih.gov/pubmed/32391914
http://dx.doi.org/10.1093/ejcts/ezaa093
Descripción
Sumario:SUMMARY: Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to understand why myocardial tissue engineering is difficult to achieve and how revascularization and contractile function could be restored in 3-dimensional bioprinted heart tissue using patient-derived stem cells.

Ejemplares similares