Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery

SUMMARY: Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to unde...

Descripción completa

Detalles Bibliográficos
Autores principales: Roche, Christopher D, Brereton, Russell J L, Ashton, Anthony W, Jackson, Christopher, Gentile, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456486/
https://www.ncbi.nlm.nih.gov/pubmed/32391914
http://dx.doi.org/10.1093/ejcts/ezaa093
_version_ 1784570877819486208
author Roche, Christopher D
Brereton, Russell J L
Ashton, Anthony W
Jackson, Christopher
Gentile, Carmine
author_facet Roche, Christopher D
Brereton, Russell J L
Ashton, Anthony W
Jackson, Christopher
Gentile, Carmine
author_sort Roche, Christopher D
collection PubMed
description SUMMARY: Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to understand why myocardial tissue engineering is difficult to achieve and how revascularization and contractile function could be restored in 3-dimensional bioprinted heart tissue using patient-derived stem cells.
format Online
Article
Text
id pubmed-8456486
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-84564862021-09-22 Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery Roche, Christopher D Brereton, Russell J L Ashton, Anthony W Jackson, Christopher Gentile, Carmine Eur J Cardiothorac Surg Review SUMMARY: Previous attempts in cardiac bioengineering have failed to provide tissues for cardiac regeneration. Recent advances in 3-dimensional bioprinting technology using prevascularized myocardial microtissues as ‘bioink’ have provided a promising way forward. This review guides the reader to understand why myocardial tissue engineering is difficult to achieve and how revascularization and contractile function could be restored in 3-dimensional bioprinted heart tissue using patient-derived stem cells. Oxford University Press 2020-05-11 /pmc/articles/PMC8456486/ /pubmed/32391914 http://dx.doi.org/10.1093/ejcts/ezaa093 Text en © The Author(s) 2020. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Review
Roche, Christopher D
Brereton, Russell J L
Ashton, Anthony W
Jackson, Christopher
Gentile, Carmine
Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery
title Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery
title_full Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery
title_fullStr Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery
title_full_unstemmed Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery
title_short Current challenges in three-dimensional bioprinting heart tissues for cardiac surgery
title_sort current challenges in three-dimensional bioprinting heart tissues for cardiac surgery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456486/
https://www.ncbi.nlm.nih.gov/pubmed/32391914
http://dx.doi.org/10.1093/ejcts/ezaa093
work_keys_str_mv AT rochechristopherd currentchallengesinthreedimensionalbioprintinghearttissuesforcardiacsurgery
AT breretonrusselljl currentchallengesinthreedimensionalbioprintinghearttissuesforcardiacsurgery
AT ashtonanthonyw currentchallengesinthreedimensionalbioprintinghearttissuesforcardiacsurgery
AT jacksonchristopher currentchallengesinthreedimensionalbioprintinghearttissuesforcardiacsurgery
AT gentilecarmine currentchallengesinthreedimensionalbioprintinghearttissuesforcardiacsurgery

Ejemplares similares