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Insulin-like growth factor 1 promotes neurological functional recovery after spinal cord injury through inhibition of autophagy via the PI3K/Akt/mTOR signaling pathway

Spinal cord injury (SCI) is a serious trauma; however, the mechanisms underlying the role of insulin-like growth factor 1 (IGF-1) in autophagy following SCI remain to be elucidated. The present study aimed to investigate the therapeutic effect of IGF-1 on SCI and to determine whether IGF-1 regulates...

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Detalles Bibliográficos
Autores principales: Zhang, Duo, Yuan, Yuan, Zhu, Jichao, Zhu, Di, Li, Chenxi, Cui, Wei, Wang, Lei, Ma, Song, Duan, Shuo, Liu, Baoge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456500/
https://www.ncbi.nlm.nih.gov/pubmed/34594402
http://dx.doi.org/10.3892/etm.2021.10700