NDRG4 sensitizes CRC cells to 5-FU by upregulating DDIT3 expression

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The incidence of colorectal cancer (CRC) has remained high in recent years, and 5-fluorouracil (5-FU) is a vital chemotherapeutic agent for its treatment. Our previous study reported that N-myc downstream-regulated gene 4 (NDRG4) plays a tumor-suppressive role in CRC, but the mechanisms associated w...

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Detalles Bibliográficos
Autores principales: Li, Ruikai, He, Chenxiang, Shen, Liangliang, Wang, Shuai, Shen, Yao, Feng, Fan, Zhang, Jian, Zheng, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456512/
https://www.ncbi.nlm.nih.gov/pubmed/34594423
http://dx.doi.org/10.3892/ol.2021.13043
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