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TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons
Midbrain dopamine (DA) neurons are slow pacemakers that maintain extracellular DA levels. During the interspike intervals, subthreshold slow depolarization underlies autonomous pacemaking and determines its rate. However, the ion channels that determine slow depolarization are unknown. Here we show...
Autores principales: | Um, Ki Bum, Hahn, Suyun, Kim, So Woon, Lee, Yoon Je, Birnbaumer, Lutz, Kim, Hyun Jin, Park, Myoung Kyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456572/ https://www.ncbi.nlm.nih.gov/pubmed/34409942 http://dx.doi.org/10.7554/eLife.70920 |
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