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Nuclear speckle specific hnRNP D-like prevents age- and AD-related cognitive decline by modulating RNA splicing

BACKGROUND: Aberrant alternative splicing plays critical role in aging and age-related diseases. Heterogeneous nuclear ribonucleoproteins (hnRNPs) reportedly regulate RNA splicing process. Whether and how hnRNPs contribute to age-related neurodegenerative diseases, especially Alzheimer’s disease (AD...

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Detalles Bibliográficos
Autores principales:	Zhang, Qingyang, Zhang, Juan, Ye, Jin, Li, Xiaohui, Liu, Hongda, Ma, Xiaolin, Wang, Chao, He, Keqiang, Zhang, Wei, Yuan, Ji, Zhao, Yingjun, Xu, Huaxi, Liu, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456587/ https://www.ncbi.nlm.nih.gov/pubmed/34551807 http://dx.doi.org/10.1186/s13024-021-00485-w

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