Concentration optimization of combinatorial drugs using Markov chain-based models

BACKGROUND: Combinatorial drug therapy for complex diseases, such as HSV infection and cancers, has a more significant efficacy than single-drug treatment. However, one key challenge is how to effectively and efficiently determine the optimal concentrations of combinatorial drugs because the number...

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Detalles Bibliográficos
Autores principales: Ma, Shuang, Dang, Dan, Wang, Wenxue, Wang, Yuechao, Liu, Lianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456646/
https://www.ncbi.nlm.nih.gov/pubmed/34548014
http://dx.doi.org/10.1186/s12859-021-04364-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456646/
https://www.ncbi.nlm.nih.gov/pubmed/34548014
http://dx.doi.org/10.1186/s12859-021-04364-5

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