Improved CRISPR/Cas9 gene editing in primary human myoblasts using low confluency cultures on Matrigel

BACKGROUND: CRISPR/Cas9 is an invaluable tool for studying cell biology and the development of molecular therapies. However, delivery of CRISPR/Cas9 components into some cell types remains a major hurdle. Primary human myoblasts are a valuable cell model for muscle studies, but are notoriously diffi...

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Detalles Bibliográficos
Autores principales: Goullée, Hayley, Taylor, Rhonda L., Forrest, Alistair R. R., Laing, Nigel G., Ravenscroft, Gianina, Clayton, Joshua S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456651/
https://www.ncbi.nlm.nih.gov/pubmed/34551826
http://dx.doi.org/10.1186/s13395-021-00278-1

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