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Suppression of CRLF1 promotes the chondrogenic differentiation of bone marrow-derived mesenchymal stem and protects cartilage tissue from damage in osteoarthritis via activation of miR-320

BACKGROUND: Osteoarthritis (OA) is the most prevalent chronic joint disease, and is hard to be cured at present. Cytokine receptor-like factor 1 (CRLF1) has been identified as an upregulated gene in OA cartilage. However, the precise identities and functions of CRLF1 in OA progression have remained...

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Detalles Bibliográficos
Autores principales:	Xu, Hao, Ding, Changrong, Guo, Cuicui, Xiang, Shuai, Wang, Yingzhen, Luo, Bing, Xiang, Hongfei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456664/ https://www.ncbi.nlm.nih.gov/pubmed/34551709 http://dx.doi.org/10.1186/s10020-021-00369-1

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