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Amphiphilic Iodine(III) Reagents for the Lipophilization of Peptides in Water

We report the functionalization of cysteine residues with lipophilic alkynes bearing a silyl group or an alkyl chain using amphiphilic ethynylbenziodoxolone reagents (EBXs). The reactions were carried out in buffer (pH 6 to 9), without organic co‐solvent or removal of oxygen, either at 37 °C or room...

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Detalles Bibliográficos
Autores principales:	Mishra, Abhaya Kumar, Tessier, Romain, Hari, Durga Prasad, Waser, Jerome
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456932/ https://www.ncbi.nlm.nih.gov/pubmed/34038604 http://dx.doi.org/10.1002/anie.202106458

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