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On the fixation or nonfixation of inversions under epistatic selection

Several recent publications have stated that epistatic fitness interactions cause the fixation of inversions that suppress recombination among the loci involved. Under this type of selection, however, the suppression of recombination in an inversion heterozygote can create a form of heterozygote adv...

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Detalles Bibliográficos
Autores principales: Charlesworth, Brian, Flatt, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456943/
https://www.ncbi.nlm.nih.gov/pubmed/34218481
http://dx.doi.org/10.1111/mec.16026
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author Charlesworth, Brian
Flatt, Thomas
author_facet Charlesworth, Brian
Flatt, Thomas
author_sort Charlesworth, Brian
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description Several recent publications have stated that epistatic fitness interactions cause the fixation of inversions that suppress recombination among the loci involved. Under this type of selection, however, the suppression of recombination in an inversion heterozygote can create a form of heterozygote advantage, which prevents the inversion from becoming fixed by selection. This process has been explicitly modelled by previous workers.
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spelling pubmed-84569432021-09-27 On the fixation or nonfixation of inversions under epistatic selection Charlesworth, Brian Flatt, Thomas Mol Ecol News and Views Several recent publications have stated that epistatic fitness interactions cause the fixation of inversions that suppress recombination among the loci involved. Under this type of selection, however, the suppression of recombination in an inversion heterozygote can create a form of heterozygote advantage, which prevents the inversion from becoming fixed by selection. This process has been explicitly modelled by previous workers. John Wiley and Sons Inc. 2021-07-04 2021-08 /pmc/articles/PMC8456943/ /pubmed/34218481 http://dx.doi.org/10.1111/mec.16026 Text en © 2021 The Authors. Molecular Ecology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle News and Views
Charlesworth, Brian
Flatt, Thomas
On the fixation or nonfixation of inversions under epistatic selection
title On the fixation or nonfixation of inversions under epistatic selection
title_full On the fixation or nonfixation of inversions under epistatic selection
title_fullStr On the fixation or nonfixation of inversions under epistatic selection
title_full_unstemmed On the fixation or nonfixation of inversions under epistatic selection
title_short On the fixation or nonfixation of inversions under epistatic selection
title_sort on the fixation or nonfixation of inversions under epistatic selection
topic News and Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456943/
https://www.ncbi.nlm.nih.gov/pubmed/34218481
http://dx.doi.org/10.1111/mec.16026
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