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On the fixation or nonfixation of inversions under epistatic selection
Several recent publications have stated that epistatic fitness interactions cause the fixation of inversions that suppress recombination among the loci involved. Under this type of selection, however, the suppression of recombination in an inversion heterozygote can create a form of heterozygote adv...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456943/ https://www.ncbi.nlm.nih.gov/pubmed/34218481 http://dx.doi.org/10.1111/mec.16026 |
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author | Charlesworth, Brian Flatt, Thomas |
author_facet | Charlesworth, Brian Flatt, Thomas |
author_sort | Charlesworth, Brian |
collection | PubMed |
description | Several recent publications have stated that epistatic fitness interactions cause the fixation of inversions that suppress recombination among the loci involved. Under this type of selection, however, the suppression of recombination in an inversion heterozygote can create a form of heterozygote advantage, which prevents the inversion from becoming fixed by selection. This process has been explicitly modelled by previous workers. |
format | Online Article Text |
id | pubmed-8456943 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-84569432021-09-27 On the fixation or nonfixation of inversions under epistatic selection Charlesworth, Brian Flatt, Thomas Mol Ecol News and Views Several recent publications have stated that epistatic fitness interactions cause the fixation of inversions that suppress recombination among the loci involved. Under this type of selection, however, the suppression of recombination in an inversion heterozygote can create a form of heterozygote advantage, which prevents the inversion from becoming fixed by selection. This process has been explicitly modelled by previous workers. John Wiley and Sons Inc. 2021-07-04 2021-08 /pmc/articles/PMC8456943/ /pubmed/34218481 http://dx.doi.org/10.1111/mec.16026 Text en © 2021 The Authors. Molecular Ecology published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | News and Views Charlesworth, Brian Flatt, Thomas On the fixation or nonfixation of inversions under epistatic selection |
title | On the fixation or nonfixation of inversions under epistatic selection |
title_full | On the fixation or nonfixation of inversions under epistatic selection |
title_fullStr | On the fixation or nonfixation of inversions under epistatic selection |
title_full_unstemmed | On the fixation or nonfixation of inversions under epistatic selection |
title_short | On the fixation or nonfixation of inversions under epistatic selection |
title_sort | on the fixation or nonfixation of inversions under epistatic selection |
topic | News and Views |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8456943/ https://www.ncbi.nlm.nih.gov/pubmed/34218481 http://dx.doi.org/10.1111/mec.16026 |
work_keys_str_mv | AT charlesworthbrian onthefixationornonfixationofinversionsunderepistaticselection AT flattthomas onthefixationornonfixationofinversionsunderepistaticselection |