Cargando…

Intracellular Protein–Drug Interactions Probed by Direct Mass Spectrometry of Cell Lysates

Understanding protein–ligand interactions in a cellular context is an important goal in molecular biology and biochemistry, and particularly for drug development. Investigators must demonstrate that drugs penetrate cells and specifically bind their targets. Towards that end, we present a native mass...

Descripción completa

Detalles Bibliográficos
Autores principales: Rogawski, Rivkah, Rogel, Adi, Bloch, Itai, Gal, Maayan, Horovitz, Amnon, London, Nir, Sharon, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457057/
https://www.ncbi.nlm.nih.gov/pubmed/34101963
http://dx.doi.org/10.1002/anie.202104947