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Intracellular Protein–Drug Interactions Probed by Direct Mass Spectrometry of Cell Lysates
Understanding protein–ligand interactions in a cellular context is an important goal in molecular biology and biochemistry, and particularly for drug development. Investigators must demonstrate that drugs penetrate cells and specifically bind their targets. Towards that end, we present a native mass...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457057/ https://www.ncbi.nlm.nih.gov/pubmed/34101963 http://dx.doi.org/10.1002/anie.202104947 |