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Intrinsically Disordered Osteopontin Fragment Orders During Interfacial Calcium Oxalate Mineralization

Calcium oxalate (CaC(2)O(4)) is the major component of kidney stone. The acidic osteopontin (OPN) protein in human urine can effectively inhibit the growth of CaC(2)O(4) crystals, thereby acting as a potent stone preventer. Previous studies in bulk solution all attest to the importance of binding an...

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Detalles Bibliográficos
Autores principales: Lu, Hao, Ng, David Yuen Wah, Lieberwirth, Ingo, Weidner, Tobias, Bonn, Mischa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457088/
https://www.ncbi.nlm.nih.gov/pubmed/34118104
http://dx.doi.org/10.1002/anie.202105768