Midkine Interaction with Chondroitin Sulfate Model Synthetic Tetrasaccharides and Their Mimetics: The Role of Aromatic Interactions

Midkine (MK) is a neurotrophic factor that participates in the embryonic central nervous system (CNS) development and neural stem cell regulation, interacting with sulfated glycosaminoglycans (GAGs). Chondroitin sulfate (CS) is the natural ligand in the CNS. In this work, we describe the interaction...

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Detalles Bibliográficos
Autores principales: García‐Jiménez, María José, Gil‐Caballero, Sergio, Maza, Susana, Corzana, Francisco, Juárez‐Vicente, Francisco, Miles, Jonathan R., Sakamoto, Kazuma, Kadomatsu, Kenji, García‐Domínguez, Mario, de Paz, José L., Nieto, Pedro M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457220/
https://www.ncbi.nlm.nih.gov/pubmed/34213045
http://dx.doi.org/10.1002/chem.202101674

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