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Enantioselective Organocatalytic Synthesis of Bicyclic Resorcinols via an Intramolecular Friedel−Crafts‐Type 1,4‐Addition: Access to Cannabidiol Analogues

The organocatalytic transformation of resorcinols is extremely rare. In this article, we report a highly enantioselective, organocatalytic intramolecular cyclization of these systems by a Friedel–Crafts‐type 1,4‐addition using a Jørgensen‐Hayashi‐like organocatalyst with a large silyl protecting gro...

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Detalles Bibliográficos
Autores principales: Bryant, Laura A., Shankland, Kenneth, Straker, Hannah E., Johnston, Callum D., Lees, Nicholas R., Cobb, Alexander J. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457227/
https://www.ncbi.nlm.nih.gov/pubmed/34594164
http://dx.doi.org/10.1002/adsc.202100647