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Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot

BACKGROUND : During repair of tetralogy of fallot (TOF) we modified surgical strategies to preserve the valve and annulus if the pulmonary valve leaflets are pliable and not significantly dysplastic. METHODS : Initially, the repair was done from the main pulmonary artery (Group-1, 215 patients) and...

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Autores principales: Dharmapuram, Anil Kumar, Ramadoss, Nagarajan, Goutami, Vejendla, Verma, Sudeep, Pande, Shantanu, Devalaraja, Sindhura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457275/
https://www.ncbi.nlm.nih.gov/pubmed/34667402
http://dx.doi.org/10.4103/apc.APC_166_20
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author Dharmapuram, Anil Kumar
Ramadoss, Nagarajan
Goutami, Vejendla
Verma, Sudeep
Pande, Shantanu
Devalaraja, Sindhura
author_facet Dharmapuram, Anil Kumar
Ramadoss, Nagarajan
Goutami, Vejendla
Verma, Sudeep
Pande, Shantanu
Devalaraja, Sindhura
author_sort Dharmapuram, Anil Kumar
collection PubMed
description BACKGROUND : During repair of tetralogy of fallot (TOF) we modified surgical strategies to preserve the valve and annulus if the pulmonary valve leaflets are pliable and not significantly dysplastic. METHODS : Initially, the repair was done from the main pulmonary artery (Group-1, 215 patients) and later through an additional incision in the infundibulum of the right ventricle (Group-2, 73 patients). Recently, we changed the approach to commissurotomy of the fused leaflets by releasing the supra valvar tethering and delamination of the cuspal apparatus till the base to improve the mobility of the cusps and do a controlled commissurotomy (Group-3, 14 patients). With delamination, we could extend the limit of the repair to a z-score of –3.5. RESULTS : There was no hospital mortality; two patients died at home after discharge. A mean follow-up of 42.01 months ± 19.25 is available for 198 patients (92%) for group 1, 16.03 ± 7.45 for group 2, and 4.07 ± 2.09 for group 3. The re-intervention-free survival is 94.4% in group 1. The z value improved from -3 (-3–-2) to -1.2 (-3 – 0), P = 0.001 in Group 1, from -2.8 (-3–-2.4) to -1 (-1.1–-0.7), P = 0.001 in Group 2 and from –3 (-4–-3) to -1, P = 0.001 in Group 3. In all the groups, there was trivial or mild pulmonary regurgitation. CONCLUSIONS : During repair of TOF, adequate valve/annulus sparing is possible if the repair is done from both the main pulmonary artery and infundibular incisions using the delamination technique.
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spelling pubmed-84572752021-10-18 Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot Dharmapuram, Anil Kumar Ramadoss, Nagarajan Goutami, Vejendla Verma, Sudeep Pande, Shantanu Devalaraja, Sindhura Ann Pediatr Cardiol Original Article BACKGROUND : During repair of tetralogy of fallot (TOF) we modified surgical strategies to preserve the valve and annulus if the pulmonary valve leaflets are pliable and not significantly dysplastic. METHODS : Initially, the repair was done from the main pulmonary artery (Group-1, 215 patients) and later through an additional incision in the infundibulum of the right ventricle (Group-2, 73 patients). Recently, we changed the approach to commissurotomy of the fused leaflets by releasing the supra valvar tethering and delamination of the cuspal apparatus till the base to improve the mobility of the cusps and do a controlled commissurotomy (Group-3, 14 patients). With delamination, we could extend the limit of the repair to a z-score of –3.5. RESULTS : There was no hospital mortality; two patients died at home after discharge. A mean follow-up of 42.01 months ± 19.25 is available for 198 patients (92%) for group 1, 16.03 ± 7.45 for group 2, and 4.07 ± 2.09 for group 3. The re-intervention-free survival is 94.4% in group 1. The z value improved from -3 (-3–-2) to -1.2 (-3 – 0), P = 0.001 in Group 1, from -2.8 (-3–-2.4) to -1 (-1.1–-0.7), P = 0.001 in Group 2 and from –3 (-4–-3) to -1, P = 0.001 in Group 3. In all the groups, there was trivial or mild pulmonary regurgitation. CONCLUSIONS : During repair of TOF, adequate valve/annulus sparing is possible if the repair is done from both the main pulmonary artery and infundibular incisions using the delamination technique. Wolters Kluwer - Medknow 2021 2021-08-11 /pmc/articles/PMC8457275/ /pubmed/34667402 http://dx.doi.org/10.4103/apc.APC_166_20 Text en Copyright: © 2021 Annals of Pediatric Cardiology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Dharmapuram, Anil Kumar
Ramadoss, Nagarajan
Goutami, Vejendla
Verma, Sudeep
Pande, Shantanu
Devalaraja, Sindhura
Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot
title Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot
title_full Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot
title_fullStr Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot
title_full_unstemmed Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot
title_short Early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of Fallot
title_sort early experience with surgical strategies aimed at preserving the pulmonary valve and annulus during repair of tetralogy of fallot
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457275/
https://www.ncbi.nlm.nih.gov/pubmed/34667402
http://dx.doi.org/10.4103/apc.APC_166_20
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