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Efficient construction of the hexacyclic ring core of palau'amine: the pK(a) concept for proceeding with unfavorable equilibrium reactions
Palau'amine has received a great deal of attention as an attractive synthetic target due to its intriguing molecular architecture and significant immunosuppressive activity, and we achieved its total synthesis in 2015. However, the synthesized palau'amine has not been readily applicable to...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457368/ https://www.ncbi.nlm.nih.gov/pubmed/34667586 http://dx.doi.org/10.1039/d1sc03260g |