Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?

Pembrolizumab and chemotherapy (chemoimmunotherapy) were administered to 2 head and neck squamous cell carcinoma (HNSCC) patients with extremely advanced local tumors and distant metastases with palliative intent. However, they demonstrated strikingly good responses and achieved remission. Expanded...

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Autores principales: Masuda, Muneyuki, Nagata, Ryozaburo, Hara, Hirotaka, Kuroki, Keiji, Sato, Kuniaki, Rikimaru, Fumihide, Toh, Satoshi, Higaki, Yuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457411/
https://www.ncbi.nlm.nih.gov/pubmed/34584700
http://dx.doi.org/10.1002/ccr3.4793
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author Masuda, Muneyuki
Nagata, Ryozaburo
Hara, Hirotaka
Kuroki, Keiji
Sato, Kuniaki
Rikimaru, Fumihide
Toh, Satoshi
Higaki, Yuichiro
author_facet Masuda, Muneyuki
Nagata, Ryozaburo
Hara, Hirotaka
Kuroki, Keiji
Sato, Kuniaki
Rikimaru, Fumihide
Toh, Satoshi
Higaki, Yuichiro
author_sort Masuda, Muneyuki
collection PubMed
description Pembrolizumab and chemotherapy (chemoimmunotherapy) were administered to 2 head and neck squamous cell carcinoma (HNSCC) patients with extremely advanced local tumors and distant metastases with palliative intent. However, they demonstrated strikingly good responses and achieved remission. Expanded application of induction chemoimmunotherapy may be useful for locally advanced HNSCC.
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spelling pubmed-84574112021-09-27 Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma? Masuda, Muneyuki Nagata, Ryozaburo Hara, Hirotaka Kuroki, Keiji Sato, Kuniaki Rikimaru, Fumihide Toh, Satoshi Higaki, Yuichiro Clin Case Rep Case Reports Pembrolizumab and chemotherapy (chemoimmunotherapy) were administered to 2 head and neck squamous cell carcinoma (HNSCC) patients with extremely advanced local tumors and distant metastases with palliative intent. However, they demonstrated strikingly good responses and achieved remission. Expanded application of induction chemoimmunotherapy may be useful for locally advanced HNSCC. John Wiley and Sons Inc. 2021-09-22 /pmc/articles/PMC8457411/ /pubmed/34584700 http://dx.doi.org/10.1002/ccr3.4793 Text en © 2021 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Masuda, Muneyuki
Nagata, Ryozaburo
Hara, Hirotaka
Kuroki, Keiji
Sato, Kuniaki
Rikimaru, Fumihide
Toh, Satoshi
Higaki, Yuichiro
Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
title Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
title_full Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
title_fullStr Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
title_full_unstemmed Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
title_short Is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
title_sort is chemoimmunotherapy a game changer in the treatment of locally advanced head and neck squamous cell carcinoma?
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457411/
https://www.ncbi.nlm.nih.gov/pubmed/34584700
http://dx.doi.org/10.1002/ccr3.4793
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