LTA4H rs2660845 association with montelukast response in early and late-onset asthma

Leukotrienes play a central pathophysiological role in both paediatric and adult asthma. However, 35% to 78% of asthmatics do not respond to leukotriene inhibitors. In this study we tested the role of the LTA4H regulatory variant rs2660845 and age of asthma onset in response to montelukast in ethnic...

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Detalles Bibliográficos
Autores principales: Maroteau, Cyrielle, Espuela-Ortiz, Antonio, Herrera-Luis, Esther, Srinivasan, Sundararajan, Carr, Fiona, Tavendale, Roger, Wilson, Karen, Hernandez-Pacheco, Natalia, Chalmers, James D., Turner, Steve, Mukhopadhyay, Somnath, Maitland-van der Zee, Anke-Hilse, Burchard, Esteban G., Pino-Yanes, Maria, Young, Simon, Lassi, Glenda, Platt, Adam, Palmer, Colin N. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457475/
https://www.ncbi.nlm.nih.gov/pubmed/34550981
http://dx.doi.org/10.1371/journal.pone.0257396

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