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Knock-down of odr-3 and ife-2 additively extends lifespan and healthspan in C. elegans

Genetic manipulations can ameliorate the aging process and extend the lifespan of model organisms. The aim of this research was to identify novel genetic interventions that promote both lifespan and healthspan, by combining the effects of multiple longevity-associated gene inactivations in C. elegan...

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Detalles Bibliográficos
Autores principales: Matei, Ioan Valentin, Samukange, Vimbai Netsai Charity, Bunu, Gabriela, Toren, Dmitri, Ghenea, Simona, Tacutu, Robi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457566/
https://www.ncbi.nlm.nih.gov/pubmed/34506301
http://dx.doi.org/10.18632/aging.203518