Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways

In this study, we investigated the role of embryonic gene Cripto-1 (CR-1) in hepatocellular carcinoma (HCC) using hepatocyte-specific CR-1-overexpressing transgenic mice. The expression of truncated 1.7-kb CR-1 transcript (SF-CR-1) was significantly higher than the full-length 2.0-kb CR-1 transcript...

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Detalles Bibliográficos
Autores principales: Liu, Yu, Li, Yan-Qing, Huang, Shi-Hao, Li, Yong-Long, Xia, Jia-Wei, Jia, Jun-Shuang, Wei, Fang, Wang, Jia-Hong, Dai, Guan-Qi, Wang, Yu-Cai, Li, Xiao-Yan, Han, Liu-Xin, Zhang, Xiao-Ling, Xiang, Xu-Dong, Zhao, Wen-Tao, Xiao, Dong, Lin, Xiao-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457585/
https://www.ncbi.nlm.nih.gov/pubmed/34517344
http://dx.doi.org/10.18632/aging.203402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457585/
https://www.ncbi.nlm.nih.gov/pubmed/34517344
http://dx.doi.org/10.18632/aging.203402

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