Cargando…
HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells
The senescence of retinal pigment epithelial (RPE) cells is associated with age-related macular degeneration (AMD), a leading cause of blindness in the world. HSP90 is a predominant chaperone that regulates cellular homeostasis under divergent physio-pathological conditions including senescence. How...
Autores principales: | Chen, Dan-Dan, Peng, Xuyan, Wang, Yuxuan, Jiang, Mingjun, Xue, Mengjiao, Shang, Guohui, Liu, Xuhui, Jia, Xiaolin, Liu, Baixue, Lu, Yingwei, Mu, Hongmei, Zhang, Fengyan, Hu, Yanzhong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457597/ https://www.ncbi.nlm.nih.gov/pubmed/34495872 http://dx.doi.org/10.18632/aging.203496 |
Ejemplares similares
-
SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway
por: Zhang, Yuhang, et al.
Publicado: (2023) -
Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin
por: Xu, Cheng, et al.
Publicado: (2021) -
Role of GDF15/MAPK14 Axis in Chondrocyte Senescence as a Novel Senomorphic Agent in Osteoarthritis
por: Weng, Pei-Wei, et al.
Publicado: (2022) -
The Therapeutic Roles of Recombinant Hsp90α on Cornea Epithelial Injury
por: Wang, Mingli, et al.
Publicado: (2022) -
Targeting Molecular Mechanism of Vascular Smooth Muscle Senescence Induced by Angiotensin II, A Potential Therapy via Senolytics and Senomorphics
por: Okuno, Keisuke, et al.
Publicado: (2020)