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The Effects of Spironolactone in Preventing Bile Duct Ligation-induced Hepatitis in A Rat Model

Cholestasis is associated with the accumulation of bile acids and bilirubin in the hepatocytes and leads to liver injury. Pregnane X Receptor (PXR) coordinates protective hepatic responses to toxic stimuli, and this receptor was reported to stimulate bile secretion by increasing MRP2 expression. Sin...

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Detalles Bibliográficos
Autores principales:	Şehirli, Ahmet Özer, Kökeş, Azime, Velioğlu-Öğünç, Ayliz, Tetik, Şermin, Özkan, Naziye, Çetinel, Şule, Sayıner, Serkan, Dülger, Gül
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457727/ https://www.ncbi.nlm.nih.gov/pubmed/34567144 http://dx.doi.org/10.22037/ijpr.2020.112488.13786

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