Molecular Insights of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole as CRF-1 Receptor Antagonists: Combined QSAR, Glide Docking, Molecular Dynamics, and In-silico ADME Studies

Stress-dependent disorders cause severe harm to human health and trigger the risk of neurodegenerative disorder. Corticotropin-releasing factor-1 receptor was found to be a potent drug target.We evaluate the essential structural residues for pharmacophore identification through 2D and 3D QSAR analys...

Descripción completa

Detalles Bibliográficos
Autores principales: Kumar, Sunil, Kumar, Neeraj, Sharma, Chandra Shekhar, Mishra, Shashank Shekher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457742/
https://www.ncbi.nlm.nih.gov/pubmed/34567143
http://dx.doi.org/10.22037/ijpr.2020.113746.14464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457742/
https://www.ncbi.nlm.nih.gov/pubmed/34567143
http://dx.doi.org/10.22037/ijpr.2020.113746.14464

Ejemplares similares