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Molecular Insights of 1,2,3,4-tetrahydropyrimido[1,2-a]benzimidazole as CRF-1 Receptor Antagonists: Combined QSAR, Glide Docking, Molecular Dynamics, and In-silico ADME Studies

Stress-dependent disorders cause severe harm to human health and trigger the risk of neurodegenerative disorder. Corticotropin-releasing factor-1 receptor was found to be a potent drug target.We evaluate the essential structural residues for pharmacophore identification through 2D and 3D QSAR analys...

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Detalles Bibliográficos
Autores principales:	Kumar, Sunil, Kumar, Neeraj, Sharma, Chandra Shekhar, Mishra, Shashank Shekher
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Shaheed Beheshti University of Medical Sciences 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457742/ https://www.ncbi.nlm.nih.gov/pubmed/34567143 http://dx.doi.org/10.22037/ijpr.2020.113746.14464

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