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Thrombopoietin from hepatocytes promotes hematopoietic stem cell regeneration after myeloablation

The bone marrow niche plays critical roles in hematopoietic recovery and hematopoietic stem cell (HSC) regeneration after myeloablative stress. However, it is not clear whether systemic factors beyond the local niche are required for these essential processes in vivo. Thrombopoietin (THPO) is a key...

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Detalles Bibliográficos
Autores principales: Gao, Longfei, Decker, Matthew, Chen, Haidee, Ding, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457823/
https://www.ncbi.nlm.nih.gov/pubmed/34463253
http://dx.doi.org/10.7554/eLife.69894