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Cost-precision trade-off relation determines the optimal morphogen gradient for accurate biological pattern formation

Spatial boundaries formed during animal development originate from the pre-patterning of tissues by signaling molecules, called morphogens. The accuracy of boundary location is limited by the fluctuations of morphogen concentration that thresholds the expression level of target gene. Producing more...

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Detalles Bibliográficos
Autores principales: Song, Yonghyun, Hyeon, Changbong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457829/
https://www.ncbi.nlm.nih.gov/pubmed/34402427
http://dx.doi.org/10.7554/eLife.70034