Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation

Immune thrombocytopenia is a consumptive coagulopathy that can be either idiopathic or associated with infectious or autoimmune etiologies. Here, we present a case of immune thrombocytopenia in the setting of acute liver failure due to coexisting diagnoses of hepatitis B virus and autoimmune hepatit...

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Autores principales: Nobuhara, Chloe, Cardona, Diana M., Arcasoy, Murat O., Berg, Carl L., Barbas, Andrew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457963/
https://www.ncbi.nlm.nih.gov/pubmed/34567820
http://dx.doi.org/10.1155/2021/8484106
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author Nobuhara, Chloe
Cardona, Diana M.
Arcasoy, Murat O.
Berg, Carl L.
Barbas, Andrew S.
author_facet Nobuhara, Chloe
Cardona, Diana M.
Arcasoy, Murat O.
Berg, Carl L.
Barbas, Andrew S.
author_sort Nobuhara, Chloe
collection PubMed
description Immune thrombocytopenia is a consumptive coagulopathy that can be either idiopathic or associated with infectious or autoimmune etiologies. Here, we present a case of immune thrombocytopenia in the setting of acute liver failure due to coexisting diagnoses of hepatitis B virus and autoimmune hepatitis. Our patient underwent orthotopic liver transplantation and recovered hemostatic platelet counts after treatment with romiplostim, a thrombopoietin receptor agonist, 51 days after transplantation. To our knowledge, this is the first case report of immune thrombocytopenia secondary to both hepatitis B virus and autoimmune hepatitis in a patient with acute liver failure.
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spelling pubmed-84579632021-09-23 Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation Nobuhara, Chloe Cardona, Diana M. Arcasoy, Murat O. Berg, Carl L. Barbas, Andrew S. Case Rep Transplant Case Report Immune thrombocytopenia is a consumptive coagulopathy that can be either idiopathic or associated with infectious or autoimmune etiologies. Here, we present a case of immune thrombocytopenia in the setting of acute liver failure due to coexisting diagnoses of hepatitis B virus and autoimmune hepatitis. Our patient underwent orthotopic liver transplantation and recovered hemostatic platelet counts after treatment with romiplostim, a thrombopoietin receptor agonist, 51 days after transplantation. To our knowledge, this is the first case report of immune thrombocytopenia secondary to both hepatitis B virus and autoimmune hepatitis in a patient with acute liver failure. Hindawi 2021-09-15 /pmc/articles/PMC8457963/ /pubmed/34567820 http://dx.doi.org/10.1155/2021/8484106 Text en Copyright © 2021 Chloe Nobuhara et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Nobuhara, Chloe
Cardona, Diana M.
Arcasoy, Murat O.
Berg, Carl L.
Barbas, Andrew S.
Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation
title Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation
title_full Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation
title_fullStr Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation
title_full_unstemmed Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation
title_short Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation
title_sort immune thrombocytopenia associated with hepatitis b virus and autoimmune hepatitis and recovery of platelet count following liver transplantation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457963/
https://www.ncbi.nlm.nih.gov/pubmed/34567820
http://dx.doi.org/10.1155/2021/8484106
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