Untargeted Metabolomic Profiling of Cuprizone-Induced Demyelination in Mouse Corpus Callosum by UPLC-Orbitrap/MS Reveals Potential Metabolic Biomarkers of CNS Demyelination Disorders

Multiple sclerosis (MS) is a neurodegenerative disorder characterized by periodic neuronal demyelination, which leads to a range of symptoms and eventually to disability. The goal of this research was to use UPLC-Orbitrap/MS to identify validated biomarkers and explore the metabolic mechanisms of MS...

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Detalles Bibliográficos
Autores principales: Zhao, Zhijie, Li, Tongqi, Dong, Xiaohua, Wang, Xiaojing, Zhang, Zhongxiao, Zhao, Changyi, Kang, Xueran, Zheng, Ruizhe, Li, Xinyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8457991/
https://www.ncbi.nlm.nih.gov/pubmed/34567412
http://dx.doi.org/10.1155/2021/7093844

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