Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design

BACKGROUND: Pooling cells from multiple biological samples prior to library preparation within the same single-cell RNA sequencing experiment provides several advantages, including lower library preparation costs and reduced unwanted technological variation, such as batch effects. Computational demu...

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Detalles Bibliográficos
Autores principales: Weber, Lukas M, Hippen, Ariel A, Hickey, Peter F, Berrett, Kristofer C, Gertz, Jason, Doherty, Jennifer Anne, Greene, Casey S, Hicks, Stephanie C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458035/
https://www.ncbi.nlm.nih.gov/pubmed/34553212
http://dx.doi.org/10.1093/gigascience/giab062

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