Cargando…

Accelerated Barrier Repair in Human Skin Explants Induced with a Plant-Derived PPAR-α Activating Complex via Cooperative Interactions

BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) govern epidermal lipid synthesis and metabolism. In skin, PPAR activation has been shown to regulate genes responsible for permeability barrier homeostasis, epidermal differentiation, lipid biosynthesis, and inflammation. OBJECTIVE: Giv...

Descripción completa

Detalles Bibliográficos
Autores principales:	Majewski, George, Craw, John, Falla, Timothy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458040/ https://www.ncbi.nlm.nih.gov/pubmed/34566418 http://dx.doi.org/10.2147/CCID.S325967

Ejemplares similares

Olive leaf‐derived PPAR agonist complex induces collagen IV synthesis in human skin models
por: Majewski, George P., et al.
Publicado: (2021)

Ex-Vivo Skin Explant Culture Is a Model for TSLP-Mediated Skin Barrier Immunity
por: Bauer, Thomas, et al.
Publicado: (2021)

Mechanisms Underlying the Functional Cooperation Between PPARα and GRα to Attenuate Inflammatory Responses
por: Bougarne, Nadia, et al.
Publicado: (2019)

PPARα-targeted mitochondrial bioenergetics mediate repair of intestinal barriers at the host–microbe intersection during SIV infection
por: Crakes, Katti R., et al.
Publicado: (2019)

Explantation of infected thoracic endovascular aortic repair
por: Fan, Emily Y., et al.
Publicado: (2018)

KLF15 and PPARα Cooperate to Regulate Cardiomyocyte Lipid Gene Expression and Oxidation
por: Prosdocimo, Domenick A., et al.
Publicado: (2015)

Impaired skin wound healing in peroxisome proliferator–activated receptor (PPAR)α and PPARβ mutant mice
por: Michalik, Liliane, et al.
Publicado: (2001)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex
por: Lemkul, Justin A., et al.
Publicado: (2015)

Migration and maturation of Langerhans cells in skin transplants and explants
Publicado: (1990)

Human skin explant model for the investigation of topical therapeutics
por: Neil, Jessica E., et al.
Publicado: (2020)

Characterization of bound water in skin hydrators prepared with and without a 3D3P interpenetrating polymer network
por: Majewski, George P., et al.
Publicado: (2018)

The Use of Amnion-Derived Cellular Cytokine Solution (ACCS) in Accelerating Closure of Interstices in Explanted Meshed Human Skin Grafts
por: Uberti, M. Georgina, et al.
Publicado: (2009)

Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils
por: Lin, Tzu-Kai, et al.
Publicado: (2017)

Solution Structures of PPARγ2/RXRα Complexes
por: Osz, Judit, et al.
Publicado: (2012)

Role of AMPK and PPARα in the anti‐skin cancer effects of ursolic acid
por: Junco, Jacob J., et al.
Publicado: (2018)

Anti-Aging and Depigmentation Effect of a Hyaluronic Acid Mechanically Stabilized Complex on Human Skin Explants
por: Siquier-Dameto, Gabriel, et al.
Publicado: (2023)

Usefulness of Skin Explants for Histologic Analysis after Fractional Photothermolysis
por: Park, Gyeong-Hun, et al.
Publicado: (2015)

Comparison of the metabolism of 10 chemicals in human and pig skin explants
por: Géniès, C., et al.
Publicado: (2018)

Metabolomics of the interaction between PPAR-α and age in the PPAR-α-null mouse
por: Atherton, Helen J, et al.
Publicado: (2009)

Allosteric Pathways in the PPARγ-RXRα nuclear receptor complex
por: Ricci, Clarisse G., et al.
Publicado: (2016)

PPARα-Independent Arterial Smooth Muscle Relaxant Effects of PPARα Agonists
por: Silswal, Neerupma, et al.
Publicado: (2012)

An Ideal PPAR Response Element Bound to and Activated by PPARα
por: Tzeng, John, et al.
Publicado: (2015)

An Innovative Fluid Dynamic System to Model Inflammation in Human Skin Explants
por: Galvan, Andrea, et al.
Publicado: (2023)

PPARα and Effects of TCE
por: Klaunig, James E., et al.
Publicado: (2007)

Scaffold-Based Pan-Agonist Design for the PPARα, PPARβ and PPARγ Receptors
por: Zhang, Li-Song, et al.
Publicado: (2012)

Discussion to: Alternative minimally invasive surgical explantation techniques for failed transcatheter mitral valve repair devices
por: Akansel, Serdar, et al.
Publicado: (2023)

Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin
por: Konger, Raymond L., et al.
Publicado: (2021)

The ethics of explantation
por: Hansson, Sven Ove
Publicado: (2021)

Establishment of a striped catfish skin explant model for studying the skin response in Aeromonas hydrophila infections
por: Siao, Ru-Fang, et al.
Publicado: (2021)

PPARα as a Transcriptional Regulator for Detoxification of Plant Diet-Derived Unfavorable Compounds
por: Ashibe, Bunichiro, et al.
Publicado: (2012)

Pericardium Plug in the Repair of the Corneoscleral Fistula After Ahmed Glaucoma Valve Explantation
por: Yoo, Chungkwon, et al.
Publicado: (2008)

Activin A Induces Langerhans Cell Differentiation In Vitro and in Human Skin Explants
por: Musso, Tiziana, et al.
Publicado: (2008)

T cells fail to develop in the human skin-cell explants system; an inconvenient truth
por: Meek, Bob, et al.
Publicado: (2011)

UV-independent induction of beta defensin 3 in neonatal human skin explants
por: Wolf Horrell, Erin, et al.
Publicado: (2015)

Prolonged viability of human organotypic skin explant in culture method (hOSEC)
por: Frade, Marco Andrey Cipriani, et al.
Publicado: (2015)

Characterization of a Topically Testable Model of Burn Injury on Human Skin Explants
por: Gross-Amat, Olivia, et al.
Publicado: (2020)

The PPARα and PPARγ Epigenetic Landscape in Cancer and Immune and Metabolic Disorders
por: Porcuna, Jesús, et al.
Publicado: (2021)

PPARα- and DEHP-Induced Cancers
por: Ito, Yuki, et al.
Publicado: (2008)

Endothelial PPARδ facilitates the post-ischemic vascular repair through interaction with HIF1α
por: Wu, Yalan, et al.
Publicado: (2022)

Cooperative cobinding of synthetic and natural ligands to the nuclear receptor PPARγ
por: Shang, Jinsai, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_b32r5f835b5pk5orp345ou2mg5