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Immune landscape, evolution, hypoxia-mediated viral mimicry pathways and therapeutic potential in molecular subtypes of pancreatic neuroendocrine tumours

OBJECTIVE: A comprehensive analysis of the immune landscape of pancreatic neuroendocrine tumours (PanNETs) was performed according to clinicopathological parameters and previously defined molecular subtypes to identify potential therapeutic vulnerabilities in this disease. DESIGN: Differential expre...

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Detalles Bibliográficos
Autores principales: Young, Kate, Lawlor, Rita T, Ragulan, Chanthirika, Patil, Yatish, Mafficini, Andrea, Bersani, Samantha, Antonello, Davide, Mansfield, David, Cingarlini, Sara, Landoni, Luca, Pea, Antonio, Luchini, Claudio, Piredda, Liliana, Kannan, Nagarajan, Nyamundanda, Gift, Morganstein, Daniel, Chau, Ian, Wiedenmann, Bertram, Milella, Michele, Melcher, Alan, Cunningham, David, Starling, Naureen, Scarpa, Aldo, Sadanandam, Anguraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458094/
https://www.ncbi.nlm.nih.gov/pubmed/32883872
http://dx.doi.org/10.1136/gutjnl-2020-321016

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