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Diet-induced alteration of intestinal stem cell function underlies obesity and prediabetes in mice

Excess nutrient uptake and altered hormone secretion in the gut contribute to a systemic energy imbalance, which causes obesity and an increased risk of type 2 diabetes and colorectal cancer. This functional maladaptation is thought to emerge at the level of the intestinal stem cells (ISCs). However...

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Detalles Bibliográficos
Autores principales:	Aliluev, Alexandra, Tritschler, Sophie, Sterr, Michael, Oppenländer, Lena, Hinterdobler, Julia, Greisle, Tobias, Irmler, Martin, Beckers, Johannes, Sun, Na, Walch, Axel, Stemmer, Kerstin, Kindt, Alida, Krumsiek, Jan, Tschöp, Matthias H., Luecken, Malte D., Theis, Fabian J., Lickert, Heiko, Böttcher, Anika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458097/ https://www.ncbi.nlm.nih.gov/pubmed/34552271 http://dx.doi.org/10.1038/s42255-021-00458-9

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