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Gabra2 is a genetic modifier of Dravet syndrome in mice

Pathogenic variants in epilepsy genes result in a spectrum of clinical severity. One source of phenotypic heterogeneity is modifier genes that affect expressivity of a primary pathogenic variant. Mouse epilepsy models also display varying degrees of clinical severity on different genetic backgrounds...

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Detalles Bibliográficos
Autores principales:	Hawkins, Nicole A., Nomura, Toshihiro, Duarte, Samantha, Barse, Levi, Williams, Robert W., Homanics, Gregg E., Mulligan, Megan K., Contractor, Anis, Kearney, Jennifer A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458207/ https://www.ncbi.nlm.nih.gov/pubmed/34086081 http://dx.doi.org/10.1007/s00335-021-09877-1

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