Increased activation product of complement 4 protein in plasma of individuals with schizophrenia

Structural variation in the complement 4 gene (C4) confers genetic risk for schizophrenia. The variation includes numbers of the increased C4A copy number, which predicts increased C4A mRNA expression. C4-anaphylatoxin (C4-ana) is a C4 protein fragment released upon C4 protein activation that has th...

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Detalles Bibliográficos
Autores principales: Kalinowski, Agnieszka, Liliental, Joanna, Anker, Lauren A., Linkovski, Omer, Culbertson, Collin, Hall, Jacob N., Pattni, Reenal, Sabatti, Chiara, Noordsy, Douglas, Hallmayer, Joachim F., Mellins, Elizabeth D., Ballon, Jacob S., O’Hara, Ruth, Levinson, Douglas F., Urban, Alexander E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458380/
https://www.ncbi.nlm.nih.gov/pubmed/34552056
http://dx.doi.org/10.1038/s41398-021-01583-5

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