Reduced B7-H3 expression by PAX3-FOXO1 knockdown inhibits cellular motility and promotes myogenic differentiation in alveolar rhabdomyosarcoma

B7-H3 (also known as CD276) is associated with aggressive characteristics in various cancers. Meanwhile, in alveolar rhabdomyosarcoma (ARMS), PAX3-FOXO1 fusion protein is associated with increased aggressiveness and poor prognosis. In the present study, we explored the relationship between PAX3-FOXO...

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Detalles Bibliográficos
Autores principales: Kanayama, Takuyo, Miyachi, Mitsuru, Sugimoto, Yohei, Yagyu, Shigeki, Kikuchi, Ken, Tsuchiya, Kunihiko, Iehara, Tomoko, Hosoi, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458399/
https://www.ncbi.nlm.nih.gov/pubmed/34552155
http://dx.doi.org/10.1038/s41598-021-98322-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458399/
https://www.ncbi.nlm.nih.gov/pubmed/34552155
http://dx.doi.org/10.1038/s41598-021-98322-z

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