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Reduced B7-H3 expression by PAX3-FOXO1 knockdown inhibits cellular motility and promotes myogenic differentiation in alveolar rhabdomyosarcoma

B7-H3 (also known as CD276) is associated with aggressive characteristics in various cancers. Meanwhile, in alveolar rhabdomyosarcoma (ARMS), PAX3-FOXO1 fusion protein is associated with increased aggressiveness and poor prognosis. In the present study, we explored the relationship between PAX3-FOXO...

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Detalles Bibliográficos
Autores principales:	Kanayama, Takuyo, Miyachi, Mitsuru, Sugimoto, Yohei, Yagyu, Shigeki, Kikuchi, Ken, Tsuchiya, Kunihiko, Iehara, Tomoko, Hosoi, Hajime
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458399/ https://www.ncbi.nlm.nih.gov/pubmed/34552155 http://dx.doi.org/10.1038/s41598-021-98322-z

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