Pan-cancer proteogenomic investigations identify post-transcriptional kinase targets

Identifying genomic alterations of cancer proteins has guided the development of targeted therapies, but proteomic analyses are required to validate and reveal new treatment opportunities. Herein, we develop a new algorithm, OPPTI, to discover overexpressed kinase proteins across 10 cancer types usi...

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Detalles Bibliográficos
Autores principales: Elmas, Abdulkadir, Tharakan, Serena, Jaladanki, Suraj, Galsky, Matthew D., Liu, Tao, Huang, Kuan-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458405/
https://www.ncbi.nlm.nih.gov/pubmed/34552204
http://dx.doi.org/10.1038/s42003-021-02636-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458405/
https://www.ncbi.nlm.nih.gov/pubmed/34552204
http://dx.doi.org/10.1038/s42003-021-02636-7

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