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The association of low body mass index with neonatal morbidities in preterm infants

Little is known about the association between body proportionality at birth and neonatal outcomes in preterm infants. Body mass index (BMI) is one of the weigh-for-length ratios that represent body proportionality. The objective of this study was to examine whether BMI at birth affects neonatal outc...

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Autores principales: Lee, Byoung Kook, Lee, Jun Hyeok, Shin, Jeongmin, Jung, Young Hwa, Choi, Chang Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458459/
https://www.ncbi.nlm.nih.gov/pubmed/34552171
http://dx.doi.org/10.1038/s41598-021-98338-5
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author Lee, Byoung Kook
Lee, Jun Hyeok
Shin, Jeongmin
Jung, Young Hwa
Choi, Chang Won
author_facet Lee, Byoung Kook
Lee, Jun Hyeok
Shin, Jeongmin
Jung, Young Hwa
Choi, Chang Won
author_sort Lee, Byoung Kook
collection PubMed
description Little is known about the association between body proportionality at birth and neonatal outcomes in preterm infants. Body mass index (BMI) is one of the weigh-for-length ratios that represent body proportionality. The objective of this study was to examine whether BMI at birth affects neonatal outcomes in preterm infants. We assessed 3115 preterm (< 30 weeks), very low birth weight (< 1500 g) infants born between January 2013 and December 2016 and registered in the Korean Neonatal Network database. Using gender-specific BMI for gestational age curves, z-scores of BMI at birth were calculated. Low-, normal-, and high-BMI were defined as BMI z-scores of less than − 1, from − 1 to 1, and greater than 1, respectively. Neonatal morbidities and mortality in low- and high-BMI groups were compared to those in normal-BMI group. The low-BMI group had an increased risk of bronchopulmonary dysplasia, bronchopulmonary dysplasia or death, and necrotizing enterocolitis after adjusting for baseline characteristics and the birth weight z-score. High-BMI group had comparable neonatal outcomes to those of normal-BMI group. Low BMI at birth was associated with an increased risk of bronchopulmonary dysplasia and necrotizing enterocolitis, whereas High BMI at birth was not associated with adverse neonatal outcomes.
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spelling pubmed-84584592021-09-24 The association of low body mass index with neonatal morbidities in preterm infants Lee, Byoung Kook Lee, Jun Hyeok Shin, Jeongmin Jung, Young Hwa Choi, Chang Won Sci Rep Article Little is known about the association between body proportionality at birth and neonatal outcomes in preterm infants. Body mass index (BMI) is one of the weigh-for-length ratios that represent body proportionality. The objective of this study was to examine whether BMI at birth affects neonatal outcomes in preterm infants. We assessed 3115 preterm (< 30 weeks), very low birth weight (< 1500 g) infants born between January 2013 and December 2016 and registered in the Korean Neonatal Network database. Using gender-specific BMI for gestational age curves, z-scores of BMI at birth were calculated. Low-, normal-, and high-BMI were defined as BMI z-scores of less than − 1, from − 1 to 1, and greater than 1, respectively. Neonatal morbidities and mortality in low- and high-BMI groups were compared to those in normal-BMI group. The low-BMI group had an increased risk of bronchopulmonary dysplasia, bronchopulmonary dysplasia or death, and necrotizing enterocolitis after adjusting for baseline characteristics and the birth weight z-score. High-BMI group had comparable neonatal outcomes to those of normal-BMI group. Low BMI at birth was associated with an increased risk of bronchopulmonary dysplasia and necrotizing enterocolitis, whereas High BMI at birth was not associated with adverse neonatal outcomes. Nature Publishing Group UK 2021-09-22 /pmc/articles/PMC8458459/ /pubmed/34552171 http://dx.doi.org/10.1038/s41598-021-98338-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Lee, Byoung Kook
Lee, Jun Hyeok
Shin, Jeongmin
Jung, Young Hwa
Choi, Chang Won
The association of low body mass index with neonatal morbidities in preterm infants
title The association of low body mass index with neonatal morbidities in preterm infants
title_full The association of low body mass index with neonatal morbidities in preterm infants
title_fullStr The association of low body mass index with neonatal morbidities in preterm infants
title_full_unstemmed The association of low body mass index with neonatal morbidities in preterm infants
title_short The association of low body mass index with neonatal morbidities in preterm infants
title_sort association of low body mass index with neonatal morbidities in preterm infants
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458459/
https://www.ncbi.nlm.nih.gov/pubmed/34552171
http://dx.doi.org/10.1038/s41598-021-98338-5
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