Cargando…
The association of low body mass index with neonatal morbidities in preterm infants
Little is known about the association between body proportionality at birth and neonatal outcomes in preterm infants. Body mass index (BMI) is one of the weigh-for-length ratios that represent body proportionality. The objective of this study was to examine whether BMI at birth affects neonatal outc...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458459/ https://www.ncbi.nlm.nih.gov/pubmed/34552171 http://dx.doi.org/10.1038/s41598-021-98338-5 |
_version_ | 1784571307816386560 |
---|---|
author | Lee, Byoung Kook Lee, Jun Hyeok Shin, Jeongmin Jung, Young Hwa Choi, Chang Won |
author_facet | Lee, Byoung Kook Lee, Jun Hyeok Shin, Jeongmin Jung, Young Hwa Choi, Chang Won |
author_sort | Lee, Byoung Kook |
collection | PubMed |
description | Little is known about the association between body proportionality at birth and neonatal outcomes in preterm infants. Body mass index (BMI) is one of the weigh-for-length ratios that represent body proportionality. The objective of this study was to examine whether BMI at birth affects neonatal outcomes in preterm infants. We assessed 3115 preterm (< 30 weeks), very low birth weight (< 1500 g) infants born between January 2013 and December 2016 and registered in the Korean Neonatal Network database. Using gender-specific BMI for gestational age curves, z-scores of BMI at birth were calculated. Low-, normal-, and high-BMI were defined as BMI z-scores of less than − 1, from − 1 to 1, and greater than 1, respectively. Neonatal morbidities and mortality in low- and high-BMI groups were compared to those in normal-BMI group. The low-BMI group had an increased risk of bronchopulmonary dysplasia, bronchopulmonary dysplasia or death, and necrotizing enterocolitis after adjusting for baseline characteristics and the birth weight z-score. High-BMI group had comparable neonatal outcomes to those of normal-BMI group. Low BMI at birth was associated with an increased risk of bronchopulmonary dysplasia and necrotizing enterocolitis, whereas High BMI at birth was not associated with adverse neonatal outcomes. |
format | Online Article Text |
id | pubmed-8458459 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-84584592021-09-24 The association of low body mass index with neonatal morbidities in preterm infants Lee, Byoung Kook Lee, Jun Hyeok Shin, Jeongmin Jung, Young Hwa Choi, Chang Won Sci Rep Article Little is known about the association between body proportionality at birth and neonatal outcomes in preterm infants. Body mass index (BMI) is one of the weigh-for-length ratios that represent body proportionality. The objective of this study was to examine whether BMI at birth affects neonatal outcomes in preterm infants. We assessed 3115 preterm (< 30 weeks), very low birth weight (< 1500 g) infants born between January 2013 and December 2016 and registered in the Korean Neonatal Network database. Using gender-specific BMI for gestational age curves, z-scores of BMI at birth were calculated. Low-, normal-, and high-BMI were defined as BMI z-scores of less than − 1, from − 1 to 1, and greater than 1, respectively. Neonatal morbidities and mortality in low- and high-BMI groups were compared to those in normal-BMI group. The low-BMI group had an increased risk of bronchopulmonary dysplasia, bronchopulmonary dysplasia or death, and necrotizing enterocolitis after adjusting for baseline characteristics and the birth weight z-score. High-BMI group had comparable neonatal outcomes to those of normal-BMI group. Low BMI at birth was associated with an increased risk of bronchopulmonary dysplasia and necrotizing enterocolitis, whereas High BMI at birth was not associated with adverse neonatal outcomes. Nature Publishing Group UK 2021-09-22 /pmc/articles/PMC8458459/ /pubmed/34552171 http://dx.doi.org/10.1038/s41598-021-98338-5 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Lee, Byoung Kook Lee, Jun Hyeok Shin, Jeongmin Jung, Young Hwa Choi, Chang Won The association of low body mass index with neonatal morbidities in preterm infants |
title | The association of low body mass index with neonatal morbidities in preterm infants |
title_full | The association of low body mass index with neonatal morbidities in preterm infants |
title_fullStr | The association of low body mass index with neonatal morbidities in preterm infants |
title_full_unstemmed | The association of low body mass index with neonatal morbidities in preterm infants |
title_short | The association of low body mass index with neonatal morbidities in preterm infants |
title_sort | association of low body mass index with neonatal morbidities in preterm infants |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8458459/ https://www.ncbi.nlm.nih.gov/pubmed/34552171 http://dx.doi.org/10.1038/s41598-021-98338-5 |
work_keys_str_mv | AT leebyoungkook theassociationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT leejunhyeok theassociationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT shinjeongmin theassociationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT jungyounghwa theassociationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT choichangwon theassociationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT leebyoungkook associationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT leejunhyeok associationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT shinjeongmin associationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT jungyounghwa associationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants AT choichangwon associationoflowbodymassindexwithneonatalmorbiditiesinpreterminfants |